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1

Antitumor studies. Part 1: Design, synthesis, antitumor activity, and AutoDock study of 2-deoxo-2-phenyl-5-deazaflavins and 2-deoxo-2-phenylflavin-5-oxides as a new class of antitumor agents

Hamed I. Ali, Keiichiro Tomita, Eiichi Akaho, Hiroto Kambara, Shinji Miura, Hiroyuki Hayakawa, Noriyuki Ashida, Yutaka Kawashima, Takehiro Yamagishi, Hisao Ikeya, Fumio Yoneda, Tomohisa Nagamatsu

Journal:

Bioorganic & Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 998 KB

english, 2007

2

First example of “diastereotopic face activation” and chiral recognition without metal assistance. A novel 5-deazaflavin enzyme model.

Tetsuji Kawamoto, Masaki Tomishima, Jun Kunitomo, Fumio Yoneda, Jun-ichi Hayami

Journal:

Tetrahedron Letters

Année:

1992

Langue:

english

Fichier:

PDF, 302 KB

english, 1992

3

Semaphorin 4D, a lymphocyte semaphorin, enhances tumor cell motility through binding its receptor, plexinB1, in pancreatic cancer

Shingo Kato, Kensuke Kubota, Takeshi Shimamura, Yoshiyasu Shinohara, Noritoshi Kobayashi, Seitaro Watanabe, Masato Yoneda, Masahiko Inamori, Fumio Nakamura, Hitoshi Ishiguro, Noboru Nakaigawa, Yoji Na

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 1.55 MB

english, 2011

4

Model of physico-chemical effect on flow accelerated corrosion in power plant

Kazutoshi Fujiwara, Masafumi Domae, Kimitoshi Yoneda, Fumio Inada

Journal:

Corrosion Science

Année:

2011

Langue:

english

Fichier:

PDF, 713 KB

english, 2011

5

Syntheses of isoalloxazines and isoalloxazine 5-oxides. A new synthesis of riboflavin

Yoneda, Fumio, Sakuma, Yoshiharu, Ichiba, Misuzu, Shinomura, Kazuko

Journal:

Journal of the American Chemical Society

Année:

1976

Langue:

english

Fichier:

PDF, 588 KB

english, 1976

6

[ASME ASME 2013 Pressure Vessels and Piping Conference - Paris, France (Sunday 14 July 2013)] Volume 6A: Materials and Fabrication - Development of Pipe Wall Thinning Evaluation Method and Prediction Tool

Yoneda, Kimitoshi, Morita, Ryo, Fujiwara, Kazutoshi, Inada, Fumio

Année:

2013

Langue:

english

Fichier:

PDF, 746 KB

english, 2013

7

Synthesis of bis(pyridodipyrimidines) as autorecycling redox catalysts and their remarkable turnover in the oxidation of alcohols

Yoneda, Fumio, Tanaka, Kiyoshi, Yamato, Hirotake, Moriyama, Kenji, Nagamatsu, Tomohisa

Journal:

Journal of the American Chemical Society

Année:

1989

Langue:

english

Fichier:

PDF, 484 KB

english, 1989

8

New synthesis of 5-deazaflavins

Yoneda, Fumio, Sakuma, Yoshiharu

Journal:

Journal of the Chemical Society Chemical Communications

Année:

1976

Langue:

english

Fichier:

PDF, 126 KB

english, 1976

9

Autorecycling oxidation of alcohols catalysed by pyridodipyrimidines as an NAD(P)+ model

Nagamatsu, Tomohisa, Yamato, Hirotake, Ono, Masami, Takarada, Shigeki, Yoneda, Fumio

Journal:

Journal of the Chemical Society Perkin Transactions 1

Année:

1992

Langue:

english

Fichier:

PDF, 1015 KB

english, 1992

10

Geroprotection in the future. In memoriam of Joseph Knoll: The selegiline story continues

Ferdinandy, Peter, Yoneda, Fumio, Muraoka, Shizuko, Fürst, Susanna, Gyires, Klara, Miklya, Ildiko

Journal:

European Journal of Pharmacology

Année:

2019

Langue:

english

Fichier:

PDF, 414 KB

english, 2019

11

ChemInform Abstract: The Facile Synthesis of 6-Azapurines by Transformation of Toxoflavins (7-Azapteridines).

Tomohisa Nagamatsu, Jun Ma, Fumio Yoneda

Journal:

Année:

2009

Fichier:

PDF, 31 KB

2009

12

Study on the structures of 2-substituted iminothiazolidine derivatives

Masatoshi Sakae, Masanori Katsurada, Mayumi Watanabe, Fumio Yoneda, Sadao Nishigaki, Toshimasa Ishida

Journal:

Journal of Heterocyclic Chemistry

Année:

1997

Fichier:

PDF, 268 KB

1997

13

The biofunctional chemistry of 5-deazaflavins and related compounds

Fumio Yoneda, Kiyoshi Tanaka

Journal:

Medicinal Research Reviews

Année:

1987

Langue:

english

Fichier:

PDF, 1.23 MB

english, 1987

14

Differences in the reaction of electron deficient olefins with organocopper(I)-Lewis acid reagents and evidence for a dianionic equivalent

Toshiro Ibuka, Takeshi Aoyagi, Kazuko Kitada, Fumio Yoneda, Yoshinori Yamamoto

Journal:

Journal of Organometallic Chemistry

Année:

1985

Langue:

english

Fichier:

PDF, 325 KB

english, 1985

15

Inhibition of shikonin biosynthesis by photodegradation products of FMN

Mamoru Tabata, Kazufumi Yazaki, Yumiko Nishikawa, Fumio Yoneda

Journal:

Année:

1993

Langue:

english

Fichier:

PDF, 359 KB

english, 1993

16

Variation of reaction channel in a flavoenzyme model with a modified pyrimidine ring

Atsuyoshi Ohno, Jun Kunitomo, Tetsuji Kawamoto, Masaki Tomishima, Kiyoshi Bessho, Fumio Yoneda

Journal:

Tetrahedron Letters

Année:

1994

Langue:

english

Fichier:

PDF, 285 KB

english, 1994

17

A theoretical study of a model of N-tert-butyl-α-phenylnitrone (PBN) as active oxygen species scavenger

Sachiko Nakai, Fumio Yoneda, Tokio Yamabe, Kenichi Fukui

Journal:

Chemical Physics

Année:

1996

Langue:

english

Fichier:

PDF, 1018 KB

english, 1996

18

A theoretical study of a model of N-tert-butyl-α-phenylnitrone (PBN) as active oxygen species scavenger (Chemical Physics 204 (1996) 313–326)

Sachiko Nakai, Fumio Yoneda, Tokio Yamabe, Kenichi Fukui

Journal:

Chemical Physics

Année:

1996

Fichier:

PDF, 35 KB

1996

19

5-deazaflavinocyclophane as a novel flavoenzyme model. Synthesis and diastereoface-differentiating reactions

Reiko Yanada, Makiko Higashikawa, Yoshihisa Miwa, Toru Taga, Fumio Yoneda

Journal:

Tetrahedron: Asymmetry

Année:

1992

Langue:

english

Fichier:

PDF, 269 KB

english, 1992

20

Effects of 10-n-Butyl-3-methyl-5-deazaflavo-6,9-quinone (5-dFlQ) on Mitochondrial Respiration

Kan-ichi Konobu, Misao Toyomoto, Yoshihiko Murai, Eriko Yamamoto, Tetsutaro Kimachi, Kiyoshi Bessho, Fumio Yoneda

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

1995

Langue:

english

Fichier:

PDF, 177 KB

english, 1995

21

Evaluation of differential hypoxic cytotoxicity and electrochemical studies of nitro 5-deazaflavins

Tetsuji Kawamoto, Yoshihiro Ikeuchi, Junko Hiraki, Yoshiteru Eikyu, Kazue Shimizu, Masaki Tomishima, Kiyoshi Bessho, Fumio Yoneda, Yuji Mikata, Mamiko Nishida, Kenji Ikehara

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

1995

Langue:

english

Fichier:

PDF, 201 KB

english, 1995

22

Synthesis and in vitro cytotoxicity of 1,2,3,4-tetrahydroisoquinoline derivatives

Toshiaki Saitoh, Kenji Abe, Masami Ishikawa, Masanao Nakatani, Seiichiro Shimazu, Noriyuki Satoh, Fumio Yoneda, Kyoji Taguchi, Yoshie Horiguchi

Journal:

European Journal of Medicinal Chemistry

Année:

2006

Langue:

english

Fichier:

PDF, 506 KB

english, 2006

23

Oxidation of thiol with 5-arylidene-1,3-dimethylbarbituric acid: application to synthesis of unsymmetrical disulfide1

Kiyoshi Tanaka, Xing Chen, Fumio Yoneda

Journal:

Année:

1988

Langue:

english

Fichier:

PDF, 555 KB

english, 1988

24

Synthesis and reaction of a new type of 5-deazaflavin with axial and planar chirality

Tetsuji Kawamoto, Kiyoshi Tanaka, Fumio Yoneda, Jun-ichi Hayami

Journal:

Tetrahedron Letters

Année:

1989

Langue:

english

Fichier:

PDF, 250 KB

english, 1989

25

Stereochemistry of asymmetric “(net) hydride transfer” in an intercoenzyme model reaction system

Tetsuji Kawamoto, Toru Taga, Kiyoshi Bessho, Fumio Yoneda, Jun-ichi Hayami

Journal:

Tetrahedron Letters

Année:

1994

Langue:

english

Fichier:

PDF, 317 KB

english, 1994

26

Diastereoface differentiating “(net) hydride transfer” in novel 5-deazaflavins modified at pyrimidine ring

Tetsuji Kawamoto, Masaki Tomishima, Fumio Yoneda, Jun-ichi Hayami

Journal:

Tetrahedron Letters

Année:

1992

Langue:

english

Fichier:

PDF, 351 KB

english, 1992

27

Stereochemistry of reaction products of 1,3-dimethylthymine epoxide with amines

Takashi Harayama, Reiko Yanada, Tooru Taga, Fumio Yoneda

Journal:

Tetrahedron Letters

Année:

1985

Langue:

english

Fichier:

PDF, 221 KB

english, 1985

28

Synthesis of viologen-tagged oligodeoxynucleotides

Yasuyoshi Iso, Fumio Yoneda, Hisafumi Ikeda, Kiyoshi Tanaka, Kaoru Fuji

Journal:

Tetrahedron Letters

Année:

1992

Langue:

english

Fichier:

PDF, 280 KB

english, 1992

29

Oxidation of thiol by 5-arylidene 1,3-dimethylbarbituric acid and its application to synthesis of unsymmetrical disulfide

Kiyoshi Tanaka, Xing Chen, Teiji Kimura, Fumio Yoneda

Journal:

Tetrahedron Letters

Année:

1987

Langue:

english

Fichier:

PDF, 214 KB

english, 1987

30

Preparation of chiral 5-deazaflavin derivatives and their asymmetric reduction of ethyl benzoylformate

Kiyoshi Tanaka, Tomoya Okada, Fumio Yoneda, Tomohisa Nagamatsu, Kazunori Kuroda

Journal:

Tetrahedron Letters

Année:

1984

Langue:

english

Fichier:

PDF, 146 KB

english, 1984

31

Reactivity of 4a,5-epoxy-5-deazaflavins

Fumio Yoneda, Yoshiharu Sakuma

Journal:

Tetrahedron Letters

Année:

1981

Langue:

english

Fichier:

PDF, 215 KB

english, 1981

32

On the pyrimidine synthesis from ethyl ethoxymethylenecyanoacetate and amidines

Sadao Nishigaki, Kyoko Aida, Keitaro Senga, Fumio Yoneda

Journal:

Tetrahedron Letters

Année:

1969

Langue:

english

Fichier:

PDF, 193 KB

english, 1969

33

Synthesis of iminodipyrimidines

Sadao Nishigaki, Keitaro Senga, Kazuko Ogiwara, Fumio Yoneda

Journal:

Tetrahedron Letters

Année:

1969

Langue:

english

Fichier:

PDF, 159 KB

english, 1969

34

A new efficient decarboxylative reduction of γ-carbamoyloxy-α,β-unsaturated esters with lithium dialkylcuprate

Toshiro Ibuka*, G. -Namg Chu, Fumio Yoneda

Journal:

Tetrahedron Letters

Année:

1984

Langue:

english

Fichier:

PDF, 244 KB

english, 1984

35

Autorecycling oxidation of alcohol catalyzed by 1,3,7,9,11,12,14-heptazapentacene-2,4,8,10 (14H,3H,9H,12H)-tetraones (mixed flavins)

Fumio Yoneda, Masakazu Koga, Toshiro Ibuka

Journal:

Tetrahedron Letters

Année:

1984

Langue:

english

Fichier:

PDF, 135 KB

english, 1984

36

Synthesis and properties of 1-benzothiopyrano[2,3-d]pyrimidine-2,4(3H)-dione (5-deaza-10-thiaflavin)

Fumio Yoneda, Michiko Kawazoe, Yoshiharu Sakuma

Journal:

Tetrahedron Letters

Année:

1978

Langue:

english

Fichier:

PDF, 330 KB

english, 1978

37

Conversion of indole into quinazoline: a new quinazoline synthesis

Fumio Yoneda, Masatsugu Higuchi, Reiko Nonaka

Journal:

Tetrahedron Letters

Année:

1973

Langue:

english

Fichier:

PDF, 101 KB

english, 1973

38

Transformation of toxoflavin into fervenulin via 1-demethyltoxoflavin

Fumio Yoneda, Tomohisa Nagamatsu

Journal:

Tetrahedron Letters

Année:

1973

Langue:

english

Fichier:

PDF, 170 KB

english, 1973

39

A convinient synthesis of toxoflavins and toxoflavin-n-oxides

Fumio Yoneda, Kazuko Shinomura, Sadao Nishigaki

Journal:

Tetrahedron Letters

Année:

1971

Langue:

english

Fichier:

PDF, 157 KB

english, 1971

40

Synthesis and reactivities of a novel flavoenzyme model, 5-deazaflavin with C2-symmetry

Reiko Yanada, Yoshiyuki Yoneda, Mikako Yazaki, Norio Mimura, Tooru Taga, Fumio Yoneda, Kazuo Yanada

Journal:

Tetrahedron: Asymmetry

Année:

1997

Langue:

english

Fichier:

PDF, 330 KB

english, 1997

41

Interaction between morphine and lysine

Sachiko Nakai, Fumio Yoneda

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2001

Langue:

english

Fichier:

PDF, 319 KB

english, 2001

42

Promotion of radiation-induced formation of 8-oxo-7,8-dihydro-2′-deoxyguanosine by nitro 5-Deazaflavin derivatives

Tetsuji Kawamoto, Yoshihiro Ikeuchi, Yuji Mikata, Maki Kishigami, Shigenobu Yano, Chieko Murayama, Tomoyuki Mori, Fumio Yoneda

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2001

Langue:

english

Fichier:

PDF, 126 KB

english, 2001

43

Synthesis and properties of oligothymidylate containing sulfur-modified thymidine: effect of thiation of pyrimidine ring on the thermostability and conformation of the duplex

Tomoyasu Ishikawa, Fumio Yoneda, Kiyoshi Tanaka, Kaoru Fuji

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

1991

Langue:

english

Fichier:

PDF, 299 KB

english, 1991

44

Synthesis and cytotoxicity of 5-deazaflavins containing o- and p-quinone moieties

Tetsutaro Kimachi, Ken-ichi Sugita, Yoshinori Tamura, Miyuki Kagawa, Kumi Yamasaki, Fumio Yoneda, Takuma Sasaki

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

1997

Langue:

english

Fichier:

PDF, 178 KB

english, 1997

45

Formation of 8-oxo-7,8-dihydro-2′-deoxyguanosine under anaerobic conditions by reductively activated nitro 5-deazaflavin derivatives

Yuji Mikata, Maki Kishigami, Mamiko Nishida, Shigenobu Yano, Tetsuji Kawamoto, Yoshihiro Ikeuchi, Fumio Yoneda

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

1999

Langue:

english

Fichier:

PDF, 269 KB

english, 1999

46

Synthesis and antitumor activities of novel 5-deazaflavin-sialic acid conjugate molecules

Yoshihiro Ikeuchi, Motoko Sumiya, Tetsuji Kawamoto *, Naoshige Akimoto, Yuji Mikata, Maki Kishigami, Shigenobu Yano, Takuma Sasaki, Fumio Yoneda *

Journal:

Bioorganic & Medicinal Chemistry

Année:

2000

Langue:

english

Fichier:

PDF, 308 KB

english, 2000

47

Enantioselective synthesis and absolute configuration of (−)-1-(benzofuran-2-yl)-2-propylaminopentane, ((−)-BPAP), a highly potent and selective catecholaminergic activity enhancer

Takahiro Oka, Takuya Yasusa, Takashi Ando, Mayumi Watanabe, Fumio Yoneda, Toshimasa Ishida, Joseph Knoll

Journal:

Bioorganic & Medicinal Chemistry

Année:

2001

Langue:

english

Fichier:

PDF, 244 KB

english, 2001

48

Theoretical investigation of (−)1-(Benzofuran-2-yl)-2-propylaminopentane [(−)-BPAP] as a hydroxyl radical scavenger

Sachiko Nakai, Fumio Yoneda

Journal:

Bioorganic & Medicinal Chemistry

Année:

2001

Langue:

english

Fichier:

PDF, 921 KB

english, 2001

49

Structure–activity studies leading to (−)1-(Benzofuran-2-yl)-2-propylaminopentane, ((−)BPAP), a highly potent, selective enhancer of the impulse propagation mediated release of Catecholamines and Serotonin in the brain

Fumio Yoneda, Toshiaki Moto, Masatoshi Sakae, Hironori Ohde, Berta Knoll, Ildikó Miklya, Joseph Knoll

Journal:

Bioorganic & Medicinal Chemistry

Année:

2001

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2001

50

Synthesis and evaluation of nitro 5-deazaflavin-pyrrolecarboxamide(s) hybrid molecules as novel DNA targeted bioreductive antitumor agents

Yoshitomo Kanaoka, Yoshihiro Ikeuchi, Tetsuji Kawamoto, Kiyoshi Bessho, Naoshige Akimoto, Yuji Mikata, Mamiko Nishida, Shigenobu Yano, Takuma Sasaki, Fumio Yoneda

Journal:

Bioorganic & Medicinal Chemistry

Année:

1998

Langue:

english

Fichier:

PDF, 224 KB

english, 1998